Genetic redundancy: Screening for selection in yeast

被引：11

作者：

Brookfield, JFY

机构：

来源：

CURRENT BIOLOGY | 1997年 / 7卷 / 06期

关键词：

D O I：

10.1016/S0960-9822(06)00176-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

An unexpectedly large proportion of eukaryotic genes yield no obvious mutant phenotype when inactivated. An ingenious new approach using yeast allows all genes to be screened simultaneously for the presence of weak selection against lack-of-function mutations.

引用

页码：R366 / R368

页数：3

共 6 条

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