The 3′ untranslated region of messenger RNA:: A molecular 'hotspot' for pathology?

被引：473

作者：

Conne, B ^{[1
]}

Stutz, A ^{[1
]}

Vassalli, JD ^{[1
]}

机构：

[1] Univ Geneva CMU, Fac Med, Dept Morphol, CH-1211 Geneva 4, Switzerland

来源：

NATURE MEDICINE | 2000年 / 6卷 / 06期

关键词：

D O I：

10.1038/76211

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

The role of the 3' untranslated region in posttranscriptional regulation of mRNA expression is being elucidated. Here we describe diseases arising from anomalies in this region, that affect the expression of one or more genes.

引用

页码：637 / 641

页数：5

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