New cytotoxic isomalabaricane-type sesterterpenes from the New Caledonian marine sponge Rhabdastrella globostellata

被引：32

作者：

Bourguet-Kondracki, ML

Longeon, A

Debitus, C

Guyot, M

机构：

[1] Museum Natl Hist Nat, CNRS, Chim Lab, F-75005 Paris, France

[2] IRD Noumea, Noumea 98848, New Caledonia

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 17期

关键词：

marine sponge; Rhabdastrella globostellata; aurorals; isomalabaricane terpenoids; cytotoxic compounds;

D O I：

10.1016/S0040-4039(00)00345-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Four new cytotoxic isomalabaricane sesterterpenes, aurorals 1-4, have been isolated from the New Caledonian marine sponge Rhabdastrella globostellata. Their structures were established by spectroscopic data including 1D and 2D techniques. These compounds were found to exhibit cytotoxic activity on KB cells. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：3087 / 3090

页数：4

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