Detection of 14-3-3 protein in the CSF of genetic Creutzfeldt-Jakob disease

被引:34
作者
Rosenmann, H
Meiner, Z
Kahana, E
Halimi, M
Lenetsky, E
Abramsky, O
Gabizon, R
机构
[1] HADASSAH UNIV HOSP,DEPT NEUROL,IL-91120 JERUSALEM,ISRAEL
[2] BEN GURION UNIV NEGEV,BARZILAI MED CTR,DEPT NEUROL,IL-84105 BEER SHEVA,ISRAEL
关键词
D O I
10.1212/WNL.49.2.593
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The 14-3-3 protein, a protein involved in signal transduction, is present in the CSF of patients with Creutzfeldt-Jakob disease (CJD) and not in patients with other dementing diseases. We show here that this is also true for patients with E200K CJD, but not for healthy carriers of the mutation.
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页码:593 / 595
页数:3
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