Seasonal variation in the incidence of deep vein thrombosis in patients with deficiency of protein C or protein S

被引：21

作者：

Bilora, F

Boccioletti, V

Manfredini, E

Petrobelli, F

Tormene, D

Simioni, P

Girolami, A

机构：

[1] Univ Padua, Sch Med, Dept Med & Surg Sci, Chair Med 2, Padua, Italy

[2] Univ Ferrara, Inst Med 1, I-44100 Ferrara, Italy

来源：

CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS | 2002年 / 8卷 / 03期

关键词：

circannual rhythm; circaseptanal rhythm; deep vein thrombosis; protein C; protein S;

D O I：

10.1177/107602960200800306

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

An attempt was made to identify circaseptanal or seasonal variation of deep vein thrombosis (DVT) in a population with protein C or protein S deficit. Forty-four patients with DVT and protein C or protein S deficit were studied for 1 year. A significant circannual rhythm was found for the total population that peaked during winter. There was also a significant falling circaseptanal rhythm on Fridays. These observations may optimize an adequate and precise anticoagulant therapy in patients with protein C or protein S deficits.

引用

页码：231 / 237

页数：7

共 17 条

[1]

CURRENT STATUS OF PULMONARY THROMBOEMBOLIC DISEASE - PATHO-PHYSIOLOGY, DIAGNOSIS, PREVENTION, AND TREATMENT [J].