The yeast Golgi apparatus: Insights and mysteries

被引:64
作者
Papanikou, Effrosyni [1 ]
Glick, Benjamin S. [1 ]
机构
[1] Univ Chicago, Chicago, IL 60637 USA
来源
FEBS LETTERS | 2009年 / 583卷 / 23期
关键词
Yeast; Golgi; Secretory pathway; Cisternal maturation; Transitional ER; TRANSITIONAL ER ORGANIZATION; DE-NOVO FORMATION; ENDOPLASMIC-RETICULUM; CISTERNAL MATURATION; PICHIA-PASTORIS; EXIT SITES; COPII COAT; IMMUNOELECTRON MICROSCOPY; SACCHAROMYCES-CEREVISIAE; SECRETORY PATHWAY;
D O I
10.1016/j.febslet.2009.10.072
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The Golgi apparatus is known to modify and sort newly synthesized secretory proteins. However, fundamental mysteries remain about the structure, operation, and dynamics of this organelle. Important insights have emerged from studying the Golgi in yeasts. For example, yeasts have provided direct evidence for Golgi cisternal maturation, a mechanism that is likely to be broadly conserved. Here, we highlight features of the yeast Golgi as well as challenges that lie ahead. (C) 2009 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:3746 / 3751
页数:6
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