学术探索
学术期刊
新闻热点
数据分析
智能评审

Mechanisms of neurotoxicity associated with amyloid beta deposition and the role of free radicals in the pathogenesis of Alzheimer's disease: A critical appraisal

被引：96
作者：
Sayre, LM
Zagorski, MG
Surewicz, WK
Krafft, GA
Perry, G
机构：
[1] CASE WESTERN RESERVE UNIV, DEPT PATHOL, CLEVELAND, OH 44106 USA
[2] NORTHWESTERN UNIV, SCH MED, DEPT BIOL CHEM & MOL PHARMACOL, CHICAGO, IL 60611 USA
来源：
CHEMICAL RESEARCH IN TOXICOLOGY | 1997年 / 10卷 / 05期
关键词：
D O I：
10.1021/tx970009n
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
[No abstract available]
引用
收藏
页码：518 / 526
页数：9
相关论文
共 141 条
[1]  
Abe K, 1996, J NEUROCHEM, V67, P2074
[2]   GIANT MULTILEVEL CATION CHANNELS FORMED BY ALZHEIMER-DISEASE AMYLOID BETA-PROTEIN [A-BETA-P-(1-40)] IN BILAYER-MEMBRANES [J].
ARISPE, N ;
POLLARD, HB ;
ROJAS, E .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (22) :10573-10577
[3]   ALZHEIMER-DISEASE AMYLOID BETA-PROTEIN FORMS CALCIUM CHANNELS IN BILAYER-MEMBRANES - BLOCKADE BY TROMETHAMINE AND ALUMINUM [J].
ARISPE, N ;
ROJAS, E ;
POLLARD, HB .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (02) :567-571
[4]   A COMPARISON OF BETA-AMYLOID (AP) DEPOSITION IN THE MEDIAL TEMPORAL-LOBE IN LATE-ONSET SPORADIC ALZHEIMERS-DISEASE, AND DOWNS-SYNDROME [J].
ARMSTRONG, RA .
AMYLOID-INTERNATIONAL JOURNAL OF EXPERIMENTAL AND CLINICAL INVESTIGATION, 1995, 2 (02) :107-113
[5]   SOLUTION CONFORMATIONS AND AGGREGATIONAL PROPERTIES OF SYNTHETIC AMYLOID BETA-PEPTIDES OF ALZHEIMERS-DISEASE - ANALYSIS OF CIRCULAR-DICHROISM SPECTRA [J].
BARROW, CJ ;
YASUDA, A ;
KENNY, PTM ;
ZAGORSKI, MG .
JOURNAL OF MOLECULAR BIOLOGY, 1992, 225 (04) :1075-1093
[6]   SOLUTION STRUCTURES OF BETA PEPTIDE AND ITS CONSTITUENT FRAGMENTS - RELATION TO AMYLOID DEPOSITION [J].
BARROW, CJ ;
ZAGORSKI, MG .
SCIENCE, 1991, 253 (5016) :179-182
[7]   VITAMIN-E PROTECTS NERVE-CELLS FROM AMYLOID BETA-PROTEIN TOXICITY [J].
BEHL, C ;
DAVIS, J ;
COLE, GM ;
SCHUBERT, D .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1992, 186 (02) :944-950
[8]   AMYLOID-BETA PEPTIDE INDUCES NECROSIS RATHER THAN APOPTOSIS [J].
BEHL, C ;
DAVIS, JB ;
KLIER, FG ;
SCHUBERT, D .
BRAIN RESEARCH, 1994, 645 (1-2) :253-264
[9]   HYDROGEN-PEROXIDE MEDIATES AMYLOID-BETA PROTEIN TOXICITY [J].
BEHL, C ;
DAVIS, JB ;
LESLEY, R ;
SCHUBERT, D .
CELL, 1994, 77 (06) :817-827
[10]  
Berg M. M., 1996, Society for Neuroscience Abstracts, V22, P486
12345678910