Longitudinal decline of the neuronal marker N-acetyl aspartate in Alzheimer's disease

被引：128

作者：

Adalsteinsson, E

Sullivan, EV

Kleinhans, N

Spielman, DM

Pfefferbaum, A

机构：

[1] SRI Int, Neuropsychiat Program BN168, Menlo Park, CA 94025 USA

[2] Stanford Univ, Sch Med, Dept Radiol, Stanford, CA 94305 USA

[3] Stanford Univ, Sch Med, Dept Psychiat & Behav Sci, Stanford, CA 94305 USA

来源：

LANCET | 2000年 / 355卷 / 9216期

关键词：

D O I：

10.1016/S0140-6736(00)02246-7

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In patients with Alzheimer's disease, but not in health controls, longitudinal magnetic resonance spectroscopy shows a striking decline in the neuronal marker, N-acetyl aspartate, despite little decline In underlying grey-matter volume.

引用

页码：1696 / 1697

页数：2

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Adalsteinsson, E ;

Spielman, D ;

Sullivan, EV ;

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[5]

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