Potential of statins for the treatment of multiple sclerosis

被引：15

作者：

Baker, D

Adamson, P

Greenwood, J

机构：

[1] UCL, Inst Neurol, Neuroinflammat Grp, London, England

[2] UCL, Inst Ophthalmol, Div Cell Biol, London, England

来源：

LANCET NEUROLOGY | 2003年 / 2卷 / 01期

关键词：

D O I：

10.1016/S1474-4422(03)00256-4

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

引用

页码：9 / 10

页数：2

共 5 条

[1] Statins as a newly recognized type of immunomodulator [J].

Kwak, B ;

Mulhaupt, F ;

Myit, S ;

Mach, F .

NATURE MEDICINE, 2000, 6 (12) :1399-1402

[2] Statins as immunomodulators -: Comparison with interferon-β1b in MS [J].

Neuhaus, O ;

Strasser-Fuchs, S ;

Fazekas, F ;

Kieseier, BC ;

Niederwieser, G ;

Hartung, HP ;

Archelos, JJ .

NEUROLOGY, 2002, 59 (07) :990-997

[3] Lovastatin treatment decreases mononuclear cell infiltration into the CNS of Lewis rats with experimental allergic encephalomyelitis [J].

Stanislaus, R ;

Singh, AK ;

Singh, I .

JOURNAL OF NEUROSCIENCE RESEARCH, 2001, 66 (02) :155-162

[4] Inhibition of Rho GTPases with protein prenyltransferase inhibitors prevents leukocyte recruitment to the central nervous system and attenuates clinical signs of disease in an animal model of multiple sclerosis [J].

Walters, CE ;

Pryce, G ;

Hankey, DJR ;

Sebti, SM ;

Hamilton, AD ;

Baker, D ;

Greenwood, J ;

Adamson, P .

JOURNAL OF IMMUNOLOGY, 2002, 168 (08) :4087-4094

[5] The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease [J].

Youssef, S ;

Stüve, O ;

Patarroyo, JC ;

Ruiz, PJ ;

Radosevich, JL ;

Hur, EM ;

Bravo, M ;

Mitchell, DJ ;

Sobel, RA ;

Steinman, L ;

Zamvil, SS .

NATURE, 2002, 420 (6911) :78-84

← 1 →