An ultrasensitive electrochemical "turn-on" label-free biosensor for Hg2+ with AuNP-functionalized reporter DNA as a signal amplifier

被引：114

作者：

Kong, Rong-Mei ^{[1
]}

Zhang, Xiao-Bing ^{[1
]}

Zhang, Liang-Liang ^{[1
]}

Jin, Xiao-Yong ^{[1
]}

Huan, Shuang-Yan ^{[1
]}

Shen, Guo-Li ^{[1
]}

Yu, Ru-Qin ^{[1
]}

机构：

[1] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2009年 / 37期

基金：

中国国家自然科学基金;

关键词：

HIGHLY SENSITIVE DETECTION; MERR FAMILY PROTEINS; BIO-BAR CODES; GOLD NANOPARTICLES; AQUEOUS-SOLUTION; SELECTIVE DETECTION; MERCURIC ION; COLORIMETRIC DETECTION; FLUORESCENT SENSOR; OPTICAL-DETECTION;

D O I：

10.1039/b911163h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A highly selective electrochemical biosensor for the ultrasensitive detection of Hg2+ in aqueous solution has been developed based on the strong and specific binding of Hg2+ by two DNA thymine bases (T-Hg2+ -T) and the use of AuNP-functionalized reporter DNA to achieve signal amplification.

引用

收藏

页码：5633 / 5635

页数：3

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