Thyroid-associated autoimmune coagulation disorders

被引：22

作者：

Franchini, Massimo ^{[1
]}

Lippi, Giuseppe ^{[2
]}

Manzato, Franco ^{[3
]}

Vescovi, Pier Paolo ^{[4
]}

机构：

[1] Univ Parma, Azienda Osped, Serv Immunoematol & Med Trasfus, Dipartimento Patol & Med Lab, I-43100 Parma, Italy

[2] Univ Verona, Sez Chim Clin, Dipartimento Sci Biomed & Morfol, I-37100 Verona, Italy

[3] Osped Carlo Poma, Lab Patol Clin, Mantua, Italy

[4] Osped Carlo Poma, Dipartimento Med, Mantua, Italy

来源：

JOURNAL OF THROMBOSIS AND THROMBOLYSIS | 2010年 / 29卷 / 01期

关键词：

IDIOPATHIC THROMBOCYTOPENIC PURPURA; GRAVES-DISEASE; ANTIPHOSPHOLIPID SYNDROME; HASHIMOTOS-THYROIDITIS; ACQUIRED HEMOPHILIA; EVANS-SYNDROME; MYASTHENIA-GRAVIS; BLOOD-COAGULATION; FACTOR-VIII; ANTICARDIOLIPIN ANTIBODIES;

D O I：

10.1007/s11239-009-0327-1

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Abnormalities of blood coagulation are not rarely observed in patients with thyroid dysfunctions and may range from subclinical laboratory abnormalities to clinically significant hemorrhagic or thrombotic complications. In this review, we summarize the current knowledge on thyroid-associated autoimmune coagulation disorders (i.e., autoimmune thrombocytopenic purpura, antiphospholipid syndrome, and autoantibodies against coagulation factor VIII) and discuss their laboratory characteristics, clinical impact, and recent progresses in the understanding of pathogenesis. Finally, we conclude that the prompt recognition of possible concomitant autoimmune coagulation disorders is important for the correct management of these patients.

引用

页码：87 / 91

页数：5

共 64 条

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VARIABLE PRESENTATION OF THROMBOCYTOPENIA IN GRAVES-DISEASE [J].