Synthesis of phosphinic and phosphonic analogs of aspartic acid

被引：9

作者：

Khomutov, AR

Osipova, TI

Khurs, EN

Alferov, KV

Khomutov, RM

机构：

[1] AN BAKH BIOCHEM INST,MOSCOW 117071,RUSSIA

[2] VA ENGELHARDT MOL BIOL INST,MOSCOW 117984,RUSSIA

来源：

RUSSIAN CHEMICAL BULLETIN | 1996年 / 45卷 / 08期

关键词：

organophosphorus analogs of amino acids; 1-amino-2-carboxyethylphosphinic acid; 2-amino-2-carboxyethylphosphinic acid;

D O I：

10.1007/BF01457787

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Approaches to the synthesis of 1-amino- and 2-amino-2-carboxyethylphosphinic and -phosphonic acids have been studied. A convenient method for the preparation of phosphinic acids is the reactions of ethyl diethoxymethylphosphonite with ethyl acetamidomethylenemalonate and ethyl 2-acetamidoacrylate.

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页码：1961 / 1964

页数：4

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