Neuropsychological correlates of Gulf War Syndrome

被引:66
作者
Hom, J
Haley, RW
Kurt, TL
机构
[1] UNIV TEXAS,SW MED CTR,DEPT NEUROL,DALLAS,TX 75235
[2] NEUROPSYCHOL CTR,DALLAS,TX
[3] UNIV TEXAS,SW MED CTR,DEPT INTERNAL MED,DALLAS,TX 75235
关键词
D O I
10.1016/S0887-6177(97)00035-8
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
As part of a comprehensive multispecialty project, the present study reports on the neurocognitive and psychological function of veterans who report Persian Gulf War-related symptoms. The neuropsychological and psychological performances of 26 ill Gulf War veterans were compared to 20 well veterans from the same military unit. Neurocognitive functions assessed included intelligence, abstraction and problem-solving, attention and concentration, memory and learning, language and visual-spatial function, and sensorimotor abilities. Psychological function was measured by self report questionnaires. Results indicated global and consistently poorer intellectual and neurocognitive function among the ill veterans compared to the control veterans. A generalized pattern of neuropsychological deficit was evident for the ill veterans. Psychological profiles of the ill veterans were similar to those in general medical patients. Based on these findings and results from the multispecialty investigation, we conclude that some of the ill veterans have experienced neurotoxic injury resulting in chronic neuropsychological impairment that is related to their service in the Persian Gulf War. (C) 1997 National Academy Neuropsychology. Published by Elsevier Science Ltd.
引用
收藏
页码:531 / 544
页数:14
相关论文
共 34 条
[1]   Neurotoxicity resulting from coexposure to pyridostigmine bromide, DEET, and permethrin: Implications of Gulf War chemical exposures [J].
AbouDonia, MB ;
Wilmarth, KR ;
Jensen, KF ;
Oehme, FW ;
Kurt, TL .
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH, 1996, 48 (01) :35-56
[2]  
ABOUDONIA MB, 1996, J TOXICOLOGY ENV HLT, V34, P201
[3]  
[Anonymous], 1995, Arch Intern Med, V155, P262
[4]  
BERG SW, 1992, UNPUB EVALUATION POS
[5]  
*COMM REV HLTH CON, 1995, HLTH CONS SERV PERS
[6]  
*DEF SCI BOARD, 1994, REP DEF SCI BOARD TA
[7]   LONG-TERM EFFECTS OF AN ORGANOPHOSPHATE UPON THE HUMAN ELECTROENCEPHALOGRAM [J].
DUFFY, FH ;
BURCHFIEL, JL ;
BARTELS, PH ;
GAON, M ;
SIM, VM .
TOXICOLOGY AND APPLIED PHARMACOLOGY, 1979, 47 (01) :161-176
[8]   Self-reported exposure to neurotoxic chemical combinations in the Gulf War - A cross-sectional epidemiologic study [J].
Haley, RW ;
Kurt, TL .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1997, 277 (03) :231-237
[9]   Evaluation of neurologic function in gulf war veterans - A blinded case-control study [J].
Haley, RW ;
Hom, J ;
Roland, PS ;
Bryan, WW ;
VanNess, PC ;
Bonte, FJ ;
Devous, MD ;
Matthews, D ;
Fleckenstein, JL ;
Wians, FH ;
Wolfe, GI ;
Kurt, TL .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1997, 277 (03) :223-230
[10]   Is there a gulf war syndrome? Searching for syndromes by factor analysis of symptoms [J].
Haley, RW ;
Kurt, TL ;
Hom, J .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1997, 277 (03) :215-222