Cytotoxic lavandulyl flavanones from Sophora flavescens

被引：122

作者：

Kang, TH ^{[1
]}

Jeong, SJ ^{[1
]}

Ko, WG ^{[1
]}

Kim, NY ^{[1
]}

Lee, BH ^{[1
]}

Inagaki, M ^{[1
]}

Miyamoto, T ^{[1
]}

Higuchi, R ^{[1
]}

Kim, YC ^{[1
]}

机构：

[1] Kyushu Univ, Fac Pharmaceut Sci, Fukuoka 8128582, Japan

来源：

JOURNAL OF NATURAL PRODUCTS | 2000年 / 63卷 / 05期

关键词：

D O I：

10.1021/np990567x

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new lavandulylated flavanones, (2S)-2'-methoxykurarinone (1) and (-)-kurarinone (2), were isolated from the root of Sophora flavescens, together with two known lavandulyl flavanones, sophoraflavanone G (3) and leachianone A (4), and two known isoflavonoids, formononetin and l-maakiain. The structures of 1 and 2 were determined on the basis of optical rotation and spectral evidence and by comparison with known compounds. Compounds 1-4 exhibited cytotoxic activity against human myeloid leukemia HL-60 cells.

引用

页码：680 / 681

页数：2

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