Temporary in situ aluminum and zinc tethering in Diels-Alder reactions

被引：36

作者：

Bertozzi, F

Olsson, R

Frejd, T

机构：

[1] ACADIA Pharmaceut AS, Synthet Chem, DK-2600 Glostrup, Denmark

[2] Univ Lund, Dept Chem, S-22100 Lund, Sweden

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 09期

关键词：

D O I：

10.1021/ol0057232

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Temporary tethering using aluminum or zinc in Diels-Alder reactions made possible the use of otherwise "noncompatible" combinations of dienes and dienophiles, resulting in the one-step formation of substituted cyclohexene 1,2-bis-methanols. Excellent regioselectivity and also significant stereoselectivity were obtained.

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页码：1283 / 1286

页数：4

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