A 5′ Leader Sequence Regulates Expression of Methanosarcinal CO Dehydrogenase/Acetyl Coenzyme A Synthase

被引：10

作者：

Anderson, Kimberly L. ^{[1
]}

Apolinario, Ethel E. ^{[1
]}

MacAuley, Sheridan R. ^{[1
]}

Sowers, Kevin R. ^{[1
]}

机构：

[1] Univ Maryland, Ctr Marine Biotechnol, Inst Biotechnol, Columbus Ctr, Baltimore, MD 21202 USA

来源：

JOURNAL OF BACTERIOLOGY | 2009年 / 191卷 / 22期

基金：

美国国家科学基金会;

关键词：

CARBON-MONOXIDE DEHYDROGENASE; ACETIVORANS C2A; MESSENGER-RNA; TRANSCRIPTION ATTENUATION; MICROARRAY ANALYSIS; ESCHERICHIA-COLI; GENE-EXPRESSION; METHANOL; ACETATE; THERMOPHILA;

D O I：

10.1128/JB.00731-09

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

In vivo expression of CO dehydrogenase/acetyl coenzyme A synthase in Methanosarcina spp. is coordinately regulated in response to substrate by at least two mechanisms: differential transcription initiation and early elongation termination near the 3' end of a 371-bp leader sequence. This is the first report of regulation of transcription elongation in the Archaea.

引用

页码：7123 / 7128

页数：6

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