DANMAP: monitoring antimicrobial resistance in Denmark

被引:76
作者
Bager, F [1 ]
机构
[1] Danish Vet Lab, DK-1790 Copenhagen, Denmark
关键词
antimicrobial siresistance; monitoring animal; food; human;
D O I
10.1016/S0924-8579(00)00135-7
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
The objectives of the Danish Integrated Antimicrobial Resistance Monitoring and Research Programme (DANMAP) are to monitor trends in resistance among bacteria from animals, food and humans, to monitor the consumption of antimicrobial agents and to determine the association between consumption and occurrence of resistance and to model transmission of resistance from animals to humans. DANMAP is based on the examination of representative bacterial isolates of animal and human pathogens, of zoonotic bacteria and of indicator bacteria. For food animals, both diseased and the healthy populations are studied. Isolates from all three reservoirs are examined for their susceptibility to a basic panel of antibiotics that includes representatives of the major classes of compounds, making comparison of resistance levels in the reservoirs possible. Isolates are stored in a strain collection and are available for further study. The data are stored in databases as MIC values or mm inhibition zones with all identifiers. A system for recording all use of the veterinary medicines, VETSTAT, is currently under implementation. For production animals, the consumption will be recorded for each herd, providing a basis for detailed modelling of the effect of consumption on resistance. (C) 2000 Elsevier Science B.V. and International Society of Chemotherapy. All rights reserved.
引用
收藏
页码:271 / 274
页数:4
相关论文
共 6 条
[1]   Occurrence of glycopeptide resistance among Enterococcus faecium isolates from conventional and ecological poultry farms [J].
Aarestrup, FM .
MICROBIAL DRUG RESISTANCE-MECHANISMS EPIDEMIOLOGY AND DISEASE, 1995, 1 (03) :255-257
[2]   FARM-ANIMALS AS A PUTATIVE RESERVOIR FOR VANCOMYCIN-RESISTANT ENTEROCOCCAL INFECTION IN MAN [J].
BATES, J ;
JORDENS, JZ ;
GRIFFITHS, DT .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1994, 34 (04) :507-514
[3]   VANA-MEDIATED HIGH-LEVEL GLYCOPEPTIDE RESISTANCE IN ENTEROCOCCUS-FAECIUM FROM ANIMAL HUSBANDRY [J].
KLARE, I ;
HEIER, H ;
CLAUS, H ;
REISSBRODT, R ;
WITTE, W .
FEMS MICROBIOLOGY LETTERS, 1995, 125 (2-3) :165-171
[4]  
1997, CONSUMPTION ANTIMICR
[5]  
1999, DANMAP 98 CONSUMPTIO
[6]  
1998, DANMAP 97 CONSUMPTIO