Ta'ta', Huayani: Perception of leishmaniasis and evaluation of medicinal plants used by the Chayahuita in Peru. Part II

被引:37
作者
Odonne, G. [1 ,2 ,3 ]
Bourdy, G. [1 ,3 ]
Castillo, D. [5 ]
Estevez, Y. [1 ,3 ]
Lancha-Tangoa, A.
Alban-Castillo, J. [4 ]
Deharo, E. [1 ,3 ]
Rojas, R. [5 ]
Stien, D. [2 ]
Sauvain, M. [1 ,3 ]
机构
[1] Univ Toulouse, UPS, UMR 152, Lab Pharmacochim Subst Nat & Pharmacophores Redox, F-31062 Toulouse 9, France
[2] Univ Antilles Guyane, CNRS, UMR EcoFoG, F-97337 Cayenne, France
[3] IRD, UMR 152, Lima, Peru
[4] Univ Nacl Mayor San Marcos, Museo Hist Nat, Lima 14, Peru
[5] UPCH, Fac Ciencias & Filosofia, Lab Invest & Desarrollo, Lima, Peru
关键词
Leishmaniasis; Medicinal plants; Traditional medicine; Chayahuita; Peru; ANTILEISHMANIAL ACTIVITY; SESQUITERPENE LACTONES; DESMODIUM-GANGETICUM; IN-VITRO; ETHNOBOTANY; CONSTITUENTS; KNOWLEDGE; SAPONINS;
D O I
10.1016/j.jep.2009.07.015
中图分类号
Q94 [植物学];
学科分类号
071001 [植物学];
摘要
Aim of the study v: A knowledge attitude and practice study centred on leishmaniasis and its treatment was performed among the Chayahuita, in Amazonian Peruvian ethnic group living in ail endemic area. This study documents traditional Chayahuita plant's use and disease concepts. Also, activity of some medicinal Plants Used by the Chayahuita is highlighted and discussed. Materials and methods: Ninety-three Chayahuita people were interviewed, following a semi-structured questionnaire focussed oil disease knowledge and perception, personal attitude and healing practices. Simultaneously, a collection of plants was performed in different ecotopes, in order to make ail extensive inventory of the pharmacopoeia. Results: For the Chayahuita, cutaneous (CL) and muco-cutaneous leishmaniasis (MCL) are considered as diseases of their own, with specific names, aetiologics, mode of transmission. Regarding CL, Chayahuita people consider that the humid characteristic of the Skill ulcer is a discriminative fact orienting the diagnostic for Ta'ta' (leishmaniasis). Forty-six different species were designated useful against LC and /or MCL (29 species by means of the questionnaire and 27 species when collecting in different ecotopes). Thirty-seven extracts corresponding to 31 Species used medicinally were screened in vitro against Leishmania amazonensis axenic amastigotes, assessing their viability by the reduction Of tetrazolium salt (MTT). Six species displayed a good activity (10 mu g/ml < IC50 < 20 mu g/ml): all undetermined hemi-epiphytic Clusiaceae. Cybianthus anthuriophyllus Pipoly (Myrsinaceae), two Piper, Piper sanguineispicum Trel., and Piper loretoanum Trel. (Piperaceae), Desmodium axillare Sw. DC. (Fabaceae), and Clibadium sylvestre (Aubl.) Baill (Asteraceae). Conclusion: Perception of leishmaniasis, attitude. treatments and diet prohibitions still largely reflects traditional Chayahuita cosmovision, even if some tentative of bio-medical re-interpretation is arising. (C) 2009 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:149 / 158
页数:10
相关论文
共 52 条
[1]
BIOCHEMICAL-CHARACTERIZATION OF LEISHMANIA-(VIANNIA)-BRAZILIENSIS AND LEISHMANIA-(VIANNIA)-PERUVIANA BY ISOENZYME ELECTROPHORESIS [J].
ARANA, M ;
EVANS, DA ;
ZOLESSI, A ;
CUENTAS, AL ;
AREVALO, J .
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1990, 84 (04) :526-529
[2]
ARRIAGADA JE, 1995, ECON BOT, V49, P328, DOI 10.1007/BF02862354
[3]
Medicinal plants uses of the Tacana, an Amazonian Bolivian ethnic group [J].
Bourdy, G ;
DeWalt, SJ ;
de Michel, LRC ;
Roca, A ;
Deharo, E ;
Muñoz, V ;
Balderrama, L ;
Quenevo, C ;
Gimenez, A .
JOURNAL OF ETHNOPHARMACOLOGY, 2000, 70 (02) :87-109
[4]
BOURDY G, 2008, YATO RAMUESH PARESHE, P345
[5]
Is there a divide between local medicinal knowledge and Western medicine? a case study among native Amazonians in Bolivia [J].
Calvet-Mir, Laura ;
Reyes-Garcia, Victoria ;
Tanner, Susan .
JOURNAL OF ETHNOBIOLOGY AND ETHNOMEDICINE, 2008, 4 (1)
[6]
Spirolactone iridoids might be responsible for the antileishmanial activity of a Peruvian traditional remedy made with Himatanthus sucuuba (Apocynaceae) [J].
Castillo, D. ;
Arevalo, J. ;
Herrera, F. ;
Ruiz, C. ;
Rojas, R. ;
Rengifo, E. ;
Vaisberg, A. ;
Lock, O. ;
Lemesre, J.-L. ;
Gornitzka, H. ;
Sauvain, M. .
JOURNAL OF ETHNOPHARMACOLOGY, 2007, 112 (02) :410-414
[7]
Behavioral effects of a neurotoxic compound isolated from Clibadium surinamense L (Asteraceae) [J].
Costa, Elson A. ;
Rocha, Fabio F. ;
Torres, Maria Luce B. ;
Souccar, Caden ;
De Lima, Thereza C. M. ;
Lapa, Antonio J. ;
Lima-Landman, Maria Teresa R. .
NEUROTOXICOLOGY AND TERATOLOGY, 2006, 28 (03) :349-353
[8]
Leishmanicidal activity of a supercritical fluid fraction obtained from Tabernaemontana catharinensis [J].
Costa Soares, Deivid ;
Pereira, Camila G. ;
Meireles, Maria Angela A. ;
Maria Saraiva, Elvira .
PARASITOLOGY INTERNATIONAL, 2007, 56 (02) :135-139
[9]
SESQUITERPENOID AND ACETYLENIC CONSTITUENTS OF 7 CLIBADIUM SPECIES [J].
CZERSON, H ;
BOHLMANN, F ;
STUESSY, TF ;
FISCHER, NH .
PHYTOCHEMISTRY, 1979, 18 (02) :257-260
[10]
DAVIES CR, 1995, EPIDEMIOL INFECT, V114, P297, DOI 10.1017/S0950268800057964