The immune response to HTLV-1

被引：137

作者：

Bangham, CRM ^{[1
]}

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Sch Med, Dept Immunol, London W2 1PG, England

来源：

CURRENT OPINION IN IMMUNOLOGY | 2000年 / 12卷 / 04期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/S0952-7915(00)00107-2

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A strong cytotoxic T lymphocyte response to HTLV-I protects against the associated inflammatory disease of the central nervous system, HAM/TSP (HTLV-I-associated myelopathy/tropical spastic paraparesis), by reducing the proviral load of HTLV-I; however, when the proviral load exceeds a threshold level, HTLV-I-specific cytotoxic T lymphocytes could contribute to inflammation.

引用

页码：397 / 402

页数：6

共 54 条

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