Natural killer cell activation receptors in innate immunity to infection

被引:30
作者
Yokoyama, WM
Scalzo, AA
机构
[1] Howard Hughes Med Inst, St Louis, MO 63110 USA
[2] Barnes Jewish Hosp, Div Rheumatol, Dept Med, St Louis, MO 63110 USA
[3] Washington Univ, Sch Med, St Louis, MO 63110 USA
[4] Univ Western Australia, Queen Elizabeth II Med Ctr, Dept Microbiol, Nedlands, WA 6009, Australia
基金
英国医学研究理事会; 美国国家卫生研究院;
关键词
NK cells; cytomegalovirus; innate immunity;
D O I
10.1016/S1286-4579(02)00034-5
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Natural killer (NK) cells are best known for their capacity to kill tumors but they are also critical in early innate responses to infection, especially herpesviruses. Recent studies indicate that NK cell receptors involved in tumor target specificity are also involved in responses to viral infections. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.
引用
收藏
页码:1513 / 1521
页数:9
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