Overview on bismuth(III) and bismuth(V) complexes with activity against Helicobacter pylori

被引：65

作者：

Dittes, U ^{[1
]}

Vogel, E ^{[1
]}

Keppler, BK ^{[1
]}

机构：

[1] UNIV VIENNA,INST ANORGAN CHEM,A-1090 VIENNA,AUSTRIA

来源：

COORDINATION CHEMISTRY REVIEWS | 1997年 / 163卷

关键词：

D O I：

10.1016/S0010-8545(97)00042-8

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Helicobacter pylori, a chronic gastritis and peptic ulcer causing bacterium, was rediscovered by Warren in 1983. The therapy to eradicate the stomach bacterium includes antibiotics, bismuth compounds and proton pump inhibitors. After the success of the classical substances bismuth subsalicylate and bismuth subcitrate, numerous efforts have been made to synthesize bismuth complexes with improved antibacterial activity. Bismuth(III) complexes with thiosemicarbazones and dithiocarbazonic methylester derivatives, and bismuth(III) and bismuth(V) tropolonato complexes have shown promising activity against Helicobacter pylori in an agar dilution test. (C) 1997 Elsevier Science S.A.

引用

页码：345 / 364

页数：20

共 47 条

[1] SYNTHESIS, STRUCTURE, AND SPECTROSCOPIC PROPERTIES OF BISMUTH CITRATE COMPOUNDS .1. CRYSTAL-STRUCTURES OF K5-X(NH4)X[BI2(CIT)2(HCIT)](H2O)Y (X = 0.25, Y = 13) AND (NH4)8[BI2(CIT)2(HCIT)2(H2O)4](H2O)2 [J].