Proteases in host cell invasion by the malaria parasite

被引：39

作者：

Blackman, MJ ^{[1
]}

机构：

[1] Natl Inst Med Res, Div Parasitol, London NW7 1AA, England

来源：

CELLULAR MICROBIOLOGY | 2004年 / 6卷 / 10期

关键词：

D O I：

10.1111/j.1462-5822.2004.00437.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The life cycle of the malaria parasite contains three distinct invasive forms, or zoites. For at least two of these - the sporozoite and the blood-stage merozoite - invasion into their respective host cell requires the activity of parasite proteases. This review summarizes the evidence for this, discusses selected well-described proteolytic modifications linked to invasion, and describes recent progress towards identifying the proteases involved.

引用

页码：893 / 903

页数：11

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