STEM CELLS The promises and perils of p53

被引：224

作者：

Krizhanovsky, Valery ^{[1
]}

Lowe, Scott W. ^{[1
]}

机构：

[1] Cold Spring Harbor Lab, Howard Hughes Med Inst, Cold Spring Harbor, NY 11724 USA

来源：

NATURE | 2009年 / 460卷 / 7259期

关键词：

GENERATION; MOUSE; FIBROBLASTS; EFFICIENCY;

D O I：

10.1038/4601085a

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Five studies show that disabling p53, an essential tumour-suppressor protein, improves the efficiency of stem-cell production. Are these results a 'heads up' that cancer cells and stem cells are disturbingly similar?

引用

页码：1085 / 1086

页数：2

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