Reduction in Staphylococcus aureus bacteraemia rates in patients receiving haemodialysis following alteration of skin antisepsis procedures

被引：11

作者：

Stewart, B. J. ^{[1
,2
]}

Gardiner, T. ^{[3
,4
]}

Perry, G. J. ^{[1
,5
]}

Tong, S. Y. C. ^{[6
]}

机构：

[1] Royal Darwin Hosp, Dept Nephrol, Darwin, NT, Australia

[2] Univ Oxford, Div Med Sci, Oxford, England

[3] Royal Darwin Hosp, Infect Prevent & Management Unit, Darwin, NT, Australia

[4] Queen Elizabeth II Hosp, Infect Control Unit, Brisbane, Qld, Australia

[5] Royal Perth Hosp, Dept Nephrol, Perth, WA 6001, Australia

[6] Menzies Sch Hlth Res, Darwin, NT, Australia

来源：

JOURNAL OF HOSPITAL INFECTION | 2016年 / 92卷 / 02期

基金：

英国医学研究理事会;

关键词：

Staphylococcus aureus; Haemodialysis; ANZDATA; Arteriovenous fistula; Central venous catheter; Chlorhexidine; BLOOD-STREAM INFECTION; PREVENTION;

D O I：

10.1016/j.jhin.2015.10.022

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

100235 [预防医学];

摘要：

This study examined all cases of Staphylococcus aureus bacteraemia (SAB) in the haemodialysis cohort at the Royal Darwin Hospital, Australia over a seven-year period. Midway through this period, antisepsis for arteriovenous fistulae (AVF) and central venous catheters (CVC) changed from 0.5% chlorhexidine solution to 2% chlorhexidine solution. Rates of SAB episodes were calculated using registry data. Trends in SAB over time were analysed using an interrupted regression analysis. Following the change to 2% chlorhexidine, average SAB rates decreased by 68%, and it is estimated that 0.111 cases of SAB/patient-year were prevented. CVC-related SAB rates remained low throughout. These results support the use of 2% chlorhexidine in skin antisepsis for patients with AVF. (C) 2015 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

引用

页码：191 / 193

页数：3

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