Activation of NF-κB and expression of COX-2 in association with neutrophil infiltration in systemic vascular tissue of women with preeclampsia

被引：83

作者：

Shah, Tanvi J. ^{[1
]}

Walsh, Scott W. ^{[1
]}

机构：

[1] Virginia Commonwealth Univ, Med Ctr, Dept Obstet & Gynecol & Physiol, Richmond, VA 23284 USA

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 2007年 / 196卷 / 01期

关键词：

COX-2; inflammation; neutrophils; NF-κB; preeclampsia;

D O I：

10.1016/j.ajog.2006.08.038

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Immunostained subcutaneous fat biopsies Were collected from normal pregnant and preeclamptic women undergoing cesarean delivery and from nonpregnant women undergoing abdominal surgery. The specimens were immunostained for neutrophils, activated nuclear factor kappa B, and COX-2. the hypothesis: that vascular infiltration of neutrophils in women with preeclampsia was associated with activation of NF-kappa B and expression of COX-2.

引用

页码：48 / 50

页数：3

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