Leukopenia and neutropenia induced by quetiapine

被引:39
作者
Cowan, Colin
Oakley, Clare
机构
关键词
antipsychotic agents; leukopenia; neutropenia; quetiapine; valproic acid;
D O I
10.1016/j.pnpbp.2006.07.003
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Leukopenia and neutropenia are recognised as side effects of antipsychotic medication, notably clozapine. A case is presented in which a female Caucasian patient who had previously developed these side effects with clozapine also developed them with quetiapine in conjunction with semisodium valproate. There was no such reaction to zuclopenthixol, sulpiride, olanzapine and aripiprazole. It is concluded that caution should be exercised when treating with quetiapine especially where there has been neutropenia with a previous antipsychotic agent. (c) 2006 Elsevier Inc. All rights reserved.
引用
收藏
页码:292 / 294
页数:3
相关论文
共 18 条
[1]
Influence of age, gender, body weight and valproate comedication on quetiapine plasma concentrations [J].
Aichhorn, W ;
Marksteiner, J ;
Walch, T ;
Zernig, G ;
Saria, A ;
Kemmler, G .
INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY, 2006, 21 (02) :81-85
[2]
Olanzapine-induced leukopenia with human leukocyte antigen profiling [J].
Buchman, N ;
Strous, RD ;
Ulman, AM ;
Lerner, M ;
Kotler, M .
INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY, 2001, 16 (01) :55-57
[3]
Quetiapine and leukopenia [J].
Clark, N ;
Weissberg, E ;
Noel, J .
AMERICAN JOURNAL OF PSYCHIATRY, 2001, 158 (05) :817-818
[4]
Clozapine treatment in Australia: a review of haematological monitoring [J].
Copolov, DL ;
Bell, WR ;
Benson, WJ ;
Keks, NA ;
Strazzeri, DC ;
Johnson, GF .
MEDICAL JOURNAL OF AUSTRALIA, 1998, 168 (10) :495-497
[5]
Acute neutropenia in a patient treated with quetiapine [J].
Croarkin, P ;
Rayner, T .
PSYCHOSOMATICS, 2001, 42 (04) :368-368
[6]
DEPAKOTE SPC, 2004, ELECT MED COMPENDIUM
[7]
Risperidone-induced leucopenia and neutropenia [J].
Dernovsek, Z ;
Tavcar, R .
BRITISH JOURNAL OF PSYCHIATRY, 1997, 171 :393-394
[8]
Risperidone-induced morning pseudoneutropenia [J].
Esposito, D ;
Corruble, E ;
Hardy, P ;
Chouinard, G .
AMERICAN JOURNAL OF PSYCHIATRY, 2005, 162 (02) :397-397
[9]
Morning pseudoneutropenia during clozapine treatment [J].
Esposito, D ;
Aouillé, J ;
Rouillon, F ;
Limosin, F .
WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY, 2003, 4 (04) :192-194
[10]
Continuing treatment with novel antipsychotic drugs despite leukopenia or thrombocytopenia [J].
Jackson, RS .
ARCHIVES OF GENERAL PSYCHIATRY, 2001, 58 (07) :706-707