Gd-loaded liposomes as T1, susceptibility, and CEST agents, all in one

被引：66

作者：

Aime, Silvio

Castelli, Daniela Delli

Lawson, Dale

Terreno, Enzo

机构：

[1] Univ Turin, Dept Chem, IFM, I-10125 Turin, Italy

[2] Univ Turin, Mol Imaging Ctr, I-10125 Turin, Italy

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2007年 / 129卷 / 09期

关键词：

D O I：

10.1021/ja0677867

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Gd-loaded nonspherical liposomes represent a new family of MRI agents that show contrast-enhancing ability upon applying different image acquisition modes. In fact they can act either as T-1- or T-2- or CEST-agents. For the first time a Gd complex is endowed with detectable shift reagent properties.

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页码：2430 / +

页数：3

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