Autism: recent molecular genetic advances

被引：108

作者：

Lamb, JA

Moore, J

Bailey, A

Monaco, AP

机构：

[1] Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford OX3 7BN, England

[2] Inst Psychiat, MRC, Child Psychiat Unit, London SE5 8AF, England

来源：

HUMAN MOLECULAR GENETICS | 2000年 / 9卷 / 06期

关键词：

D O I：

10.1093/hmg/9.6.861

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Autism (MIM 209850) is a severe neuropsychiatric disorder of unknown aetiology with profound consequences for patients and their families. Strong evidence from twin and family studies indicates the importance of genetic factors in the development of idiopathic autism, although it is clear that these influences are complex. This review focuses on recent molecular investigations to identify susceptibility loci implicated in autistic disorder.

引用

页码：861 / 868

页数：8

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