Sepsis: the critical role of iron

被引:65
作者
Bullen, J
Griffiths, E
Rogers, H
Ward, G
机构
[1] Univ Miami, Sch Med, Dept Surg, Miami, FL 33101 USA
[2] WHO, CH-1211 Geneva 27, Switzerland
[3] Langton Cottage, Suffolk IP23 7HL, England
关键词
sepsis; iron; infection;
D O I
10.1016/S1286-4579(00)00326-9
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Sepsis is a global problem which is exacerbated by increasing bacterial resistance to antibiotics, However, mechanisms of natural resistance can be extremely effective, and need to be exploited, but the availability of iron is critical for controlling bacterial growth. The diagnosis of sepsis and possible strategies for limiting iron availability are discussed. (C) 2000 Editions scientifiques et medicales Elsevier SAS.
引用
收藏
页码:409 / 415
页数:7
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