Economic considerations in the production of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) by bacterial fermentation

被引:37
作者
Choi, J
Lee, SY
机构
[1] Korea Adv Inst Sci & Technol, Dept Chem Engn, Yusong Gu, Taejon 305701, South Korea
[2] Korea Adv Inst Sci & Technol, BioProc Engn Res Ctr, Yusong Gu, Taejon 305701, South Korea
关键词
D O I
10.1007/s002530000326
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The process for the production of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) [P(3HB/V)] by bacterial fermentation and its recovery was analysed. The effects of various factors such as P(3HB/V) content, P(3HB/V) productivity, P(3HB/V) yield and 3-hydroxyvalerate (3HV) fraction in P(3HB/V) on the production cost of P(3HB/V) were examined. The increase in the 3HV yield on a carbon source did not significantly decrease the production cost when the 3HV fraction was 10 mol%, because the cost of the carbon substrate for 3HV was relatively small in terms of the total cost. However, at a 3HV fraction of 30 mol%, the 3HV yield on a carbon source had a significant effect on the total P(3HB/V) production cost. The production cost of P(3HB/V) increased linearly with the increase in the 3HV fraction in P(3HB/V).
引用
收藏
页码:646 / 649
页数:4
相关论文
共 21 条
[1]   OCCURRENCE, METABOLISM, METABOLIC ROLE, AND INDUSTRIAL USES OF BACTERIAL POLYHYDROXYALKANOATES [J].
ANDERSON, AJ ;
DAWES, EA .
MICROBIOLOGICAL REVIEWS, 1990, 54 (04) :450-472
[2]  
[Anonymous], MANUAL IND MICROBIOL
[3]   POLYMER SYNTHESIS BY MICROORGANISMS - TECHNOLOGY AND ECONOMICS [J].
BYROM, D .
TRENDS IN BIOTECHNOLOGY, 1987, 5 (09) :246-250
[4]   Factors affecting the economics of polyhydroxyalkanoate production by bacterial fermentation [J].
Choi, J ;
Lee, SY .
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 1999, 51 (01) :13-21
[5]  
Choi JI, 1999, APPL ENVIRON MICROB, V65, P4363
[6]  
Choi JI, 1999, BIOTECHNOL BIOENG, V62, P546, DOI 10.1002/(SICI)1097-0290(19990305)62:5<546::AID-BIT6>3.0.CO
[7]  
2-0
[8]   Process analysis and economic evaluation for poly(3-hydroxybutyrate) production by fermentation [J].
Choi, JI ;
Lee, SY .
BIOPROCESS ENGINEERING, 1997, 17 (06) :335-342
[9]  
Doi Y., 1990, MICROBIAL POLYESTERS
[10]   Efficient production of medium-chain-length poly(3-hydroxyalkanoates) from octane by Pseudomonas oleovorans: economic considerations [J].
Hazenberg, W ;
Witholt, B .
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 1997, 48 (05) :588-596