Drug Therapy Use of Diuretics in Patients with Hypertension

被引:162
作者
Ernst, Michael E. [1 ,2 ]
Moser, Marvin [3 ]
机构
[1] Univ Iowa, Coll Pharm, Dept Pharm Practice & Sci, Iowa City, IA 52242 USA
[2] Univ Iowa, Dept Family Med, Carver Coll Med, Iowa City, IA USA
[3] Yale Univ, Sch Med, Sect Cardiovasc Med, New Haven, CT USA
关键词
LIPID-LOWERING TREATMENT; ISOLATED SYSTOLIC HYPERTENSION; HIGH-BLOOD-PRESSURE; PROSPECTIVELY-DESIGNED OVERVIEWS; MAJOR CARDIOVASCULAR EVENTS; JOINT NATIONAL COMMITTEE; LONG-TERM; ANTIHYPERTENSIVE TREATMENT; CLINICAL-OUTCOMES; RESISTANT HYPERTENSION;
D O I
10.1056/NEJMra0907219
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
This review focuses on thiazides, the diuretics most often indicated for long-term therapy for hypertension. Thiazide diuretics reduce blood pressure when administered as monotherapy; thiazides also enhance the efficacy of other antihypertensive agents and can reduce hypertension-related morbidity and mortality. Copyright © 2009 Massachusetts Medical Society.
引用
收藏
页码:2153 / 2164
页数:12
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