Fn-type chicory inulin hydrolysate has a prebiotic effect in humans

被引:108
作者
Menne, E
Guggenbuhl, N
Roberfroid, M [1 ]
机构
[1] Univ Catholique Louvain, B-1200 Brussels, Belgium
[2] Inst Paul Lambin, B-1200 Brussels, Belgium
关键词
prebiotics; inulin; oligofructose; humans;
D O I
10.1093/jn/130.5.1197
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
The partial enzymatic hydrolysis of chicory inulin (GFn; 2 less than or equal to n less than or equal to 60) yields an oligofructose preparation that is composed of both GFn-type and Fn-type oligosaccharides (2 less than or equal to n less than or equal to 7; 2 less than or equal to m less than or equal to 7), where G is glucose, F is fructose, and n is the number of beta(2-->1) bound fructose moieties. Human studies have shown that feeding GFn-type oligomers significantly modifies the composition of the fecal microflora especially by increasing the number of bifidobacteria. The experiments reported here were used to test the hypothesis that the Fn-type molecules have the same property. During a controlled feeding study, 8 volunteers (5 females and 3 males) consumed 8 g/d of an Fn-rich product for up to 5 wk. Fecal samples were collected and analyzed for total anaerobes, bifidobacteria, lactobacilli, bacteroides, coliforms and Clostridium perfringens. Both 2 and 5 wk of oligofructose feeding resulted in a selective increase in bifidobacteria (P < 0.01). In addition, a daily intake of 8 g of the Fn-type oligofructose preparation reduced fecal pH and caused little intestinal discomfort.
引用
收藏
页码:1197 / 1199
页数:3
相关论文
共 14 条
[1]  
[Anonymous], 1997, The large intestine in nutrition and disease
[2]   AN ELECTIVE AND SELECTIVE ISOLATION MEDIUM FOR BIFIDOBACTERIUM SPP [J].
BEERENS, H .
LETTERS IN APPLIED MICROBIOLOGY, 1990, 11 (03) :155-157
[3]   Dietary supplement of neosugar alters the fecal flora and decreases activities of some reductive enzymes in human subjects [J].
Buddington, RK ;
Williams, CH ;
Chen, SC ;
Witherly, SA .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1996, 63 (05) :709-716
[4]  
DELEENHEER L, 1994, STARCH-STARKE, V46, P193
[5]  
DENHOND EM, 2000, IN PRESS NUTR RES
[6]   SELECTIVE STIMULATION OF BIFIDOBACTERIA IN THE HUMAN COLON BY OLIGOFRUCTOSE AND INULIN [J].
GIBSON, GR ;
BEATTY, ER ;
WANG, X ;
CUMMINGS, JH .
GASTROENTEROLOGY, 1995, 108 (04) :975-982
[7]   DIETARY MODULATION OF THE HUMAN COLONIC MICROBIOTA - INTRODUCING THE CONCEPT OF PREBIOTICS [J].
GIBSON, GR ;
ROBERFROID, MB .
JOURNAL OF NUTRITION, 1995, 125 (06) :1401-1412
[8]  
GIBSON GR, 1999, COLONIC MICROBIOTA N, P101, DOI DOI 10.1007/978-94-017-1079-4
[9]   Effects of inulin and lactose on fecal microflora, microbial activity, and bowel habit in elderly constipated persons [J].
Kleessen, B ;
Sykura, B ;
Zunft, HJ ;
Blaut, M .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1997, 65 (05) :1397-1402
[10]   The bifidogenic nature of chicory inulin and its hydrolysis products [J].
Roberfroid, MB ;
Van Loo, JAE ;
Gibson, GR .
JOURNAL OF NUTRITION, 1998, 128 (01) :11-19