Efficient, highly stereocontrolled first synthesis of (-)-9-acetoxyfukinanolide from enantiopure 1,6-dimethylcyclohexene

被引：7

作者：

Hamelin, O ^{[1
]}

Depres, JP ^{[1
]}

Heidenhain, S ^{[1
]}

Greene, AE ^{[1
]}

机构：

[1] UNIV GRENOBLE 1,LEDSS,F-38041 GRENOBLE 9,FRANCE

来源：

NATURAL PRODUCT LETTERS | 1997年 / 10卷 / 02期

关键词：

bakkane; dichloroketene; cycloaddition; beta-methylene-gamma-butyrolactonization;

D O I：

10.1080/10575639708043722

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A particularly efficacious first preparation of enantiopure (-)-9-acetoxyfukinanolide has been carried out that is based on a stereoselective dichloroketene-1,6-dimethylcyclohexene cycloaddition reaction and effective free-radical beta-methylene-gamma-butyrolactonization and retroaldol-aldol processes.

引用

收藏

页码：99 / 103

页数：5

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