Synthesis of 1,2-difunctionalized fine chemicals through catalytic, enantioselective ring-opening reactions of epoxides

被引：190

作者：

Schneider, Christoph ^{[1
]}

机构：

[1] Univ Leipzig, Inst Organ Chem, D-04103 Leipzig, Germany

来源：

SYNTHESIS-STUTTGART | 2006年 / 23期

关键词：

asymmetric synthesis; desymmetrization; enzymes; epoxides; kinetic resolution;

D O I：

10.1055/s-2006-950348

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This review summarizes the development of metal- and enzyme-catalyzed, enantioselective ring-opening reactions of meso-epoxides and racemic epoxides with various hetero and carbon nucleophiles towards the synthesis of highly enantiomerically enriched 1,2-difunctionalized fine chemicals.

引用

页码：3919 / 3944

页数：26

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