Context-specific roles of EMT programmes in cancer cell dissemination

被引：87

作者：

Angela Nieto, M. ^{[1
]}

机构：

[1] CSIC UMH, Inst Neurociencias, Ave Ramon y Cajal S-N, Sant Joan dAlacant 03550, Spain

来源：

NATURE CELL BIOLOGY | 2017年 / 19卷 / 05期

关键词：

EPITHELIAL-MESENCHYMAL TRANSITION; BREAST-CANCER; METASTASIS; EXPRESSION; CHEMORESISTANCE; REPRESSION; PLASTICITY; INVASION; ZEB1;

D O I：

10.1038/ncb3520

中图分类号：

Q2 [细胞生物学];

学科分类号：

071013 [干细胞生物学];

摘要：

The role of the epithelial-to-mesenchymal transition in tumour progression remains a topic of intense debate. Now, data on the role of Zeb1 in the metastatic spread of pancreatic cancer clarify apparently conflicting views by revealing context-specific, differential use of individual epithelial-to-mesenchymal transition transcription factors in cancer cell dissemination.

引用

页码：416 / 418

页数：3

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