Pertussis in the Netherlands: An outbreak despite high levels of immunization with whole-cell vaccine

被引:114
作者
deMelker, HE [1 ]
ConynvanSpaendonck, MAE [1 ]
Rumke, H [1 ]
vanWijngaarden, JK [1 ]
Mooi, FR [1 ]
Schellekens, JFP [1 ]
机构
[1] INSPECTORATE HLTH,RIJSWIJK,NETHERLANDS
关键词
D O I
10.3201/eid0302.970211
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
In 1996, a sudden increase in pertussis incidence was reported in the Netherlands (2.1 per 100,000 in 1995, 18 per 100,000 in 1996). Although not all potential surveillance artifacts could be excluded, it is highly probable that the data reflect a true outbreak. However, the cause of this increase has not yet been determined. Further research is directed to the severity of disease and a possible mismatch between the vaccine and the circulating Bordetella strains.
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页码:175 / 178
页数:4
相关论文
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