TwoB or not twoB: differential transmission at glutamatergic mossy fiber-interneuron synapses in the hippocampus

被引：24

作者：

Bischofberger, J ^{[1
]}

Jonas, P ^{[1
]}

机构：

[1] Univ Freiburg, Inst Physiol, D-79104 Freiburg, Germany

来源：

TRENDS IN NEUROSCIENCES | 2002年 / 25卷 / 12期

关键词：

D O I：

10.1016/S0166-2236(02)02259-2

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Mossy fiber (MF) synapses are key stations for flow of information through the hippocampal formation. A major component of the output of the MF system is directed towards inhibitory interneurons. Recent studies have revealed that the functional properties of MF-interneuron synapses differ substantially from those of MF-CA3 pyramidal neuron synapses. Mossy-fiber-interneuron synapses in the stratum lucidum represent a continuum of functional subtypes, in which the subunit composition of postsynaptic AMPA receptors and NMDA receptors appears to be regulated in a coordinated manner.

引用

页码：600 / 603

页数：4

共 26 条

[1]

Acsády L, 1998, J NEUROSCI, V18, P3386

[2] PTP and LTP at a hippocampal mossy fiber-interneuron synapse [J].

Alle, H ;

Jonas, P ;

Geiger, JRP .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (25) :14708-14713

[3] Subunit-specific NMDA receptor trafficking to synapses [J].

Barria, A ;

Malinow, R .

NEURON, 2002, 35 (02) :345-353

[4] NMDA AND NON-NMDA RECEPTORS ARE CO-LOCALIZED AT INDIVIDUAL EXCITATORY SYNAPSES IN CULTURED RAT HIPPOCAMPUS [J].

BEKKERS, JM ;

STEVENS, CF .

NATURE, 1989, 341 (6239) :230-233

[5]

BISCHOFBERGER J, IN PRESS J NEUROSCI

[6] 3-DIMENSIONAL ANALYSIS OF THE STRUCTURE AND COMPOSITION OF CA3 BRANCHED DENDRITIC SPINES AND THEIR SYNAPTIC RELATIONSHIPS WITH MOSSY FIBER BOUTONS IN THE RAT HIPPOCAMPUS [J].

CHICUREL, ME ;

HARRIS, KM .

JOURNAL OF COMPARATIVE NEUROLOGY, 1992, 325 (02) :169-182

[7]

Dingledine R, 1999, PHARMACOL REV, V51, P7

[8] EPSP amplification and the precision of spike timing in hippocampal neurons [J].

Fricker, D ;

Miles, R .

NEURON, 2000, 28 (02) :559-569

[9] DIVERGENCE OF HIPPOCAMPAL MOSSY FIBERS [J].

FROTSCHER, M ;

SORIANO, E ;

MISGELD, U .

SYNAPSE, 1994, 16 (02) :148-160

[10] Dynamic control of presynaptic ca2+inflow by fast-inactivating K+ channels in hippocampal mossy fiber boutons [J].

Geiger, JRP ;

Jonas, P .

NEURON, 2000, 28 (03) :927-939

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