Ultrasound-triggered smart drug release from a poly(dimethylsiloxane)-mesoporous silica composite

被引：215

作者：

Kim, Hyun-Jong ^{[1
]}

Matsuda, Hirofumi ^{[1
]}

Zhou, Haoshen ^{[1
]}

Honma, Itaru ^{[1
]}

机构：

[1] Natl Inst Adv Ind Sci & Technol, Energy Technol Res Inst, Nanoenergy Mat Grp, Tsukuba, Ibaraki 3058568, Japan

来源：

ADVANCED MATERIALS | 2006年 / 18卷 / 23期

关键词：

D O I：

10.1002/adma.200600387

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Ultrasound is used as an external trigger for the pulsatile release of the drug ibuprofen. The system is composed of mesoporous silica as the drug reservoir and poly(dimethylsiloxane) (PDMS) as an implantable body. This system could find use for in vivo delivery of drugs in response to changes in physiological conditions.

引用

页码：3083 / +

页数：7

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