Infrared absorption and vibrational circular dichroism spectra of selected deoxyoctanucleotides complexed with daunorubicin

被引：17

作者：

Maharaj, V

Rauk, A

vandeSande, JH

Wieser, H

机构：

[1] UNIV CALGARY, FAC SCI, DEPT CHEM, CALGARY, AB T2N 1N4, CANADA

[2] UNIV CALGARY, FAC MED, DEPT BIOCHEM MED, CALGARY, AB T2N 1N4, CANADA

来源：

JOURNAL OF MOLECULAR STRUCTURE | 1997年 / 408卷

关键词：

infrared absorption spectroscopy; infrared vibrational circular dichroism; deoxyoctanucleotides; daunorubicin;

D O I：

10.1016/S0022-2860(96)09668-8

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Infrared absorption and vibrational circular dichroism (VCD) spectra of d(CGCGCGCG)d(CGCGCGCG) and d(CGTATACG)d(CGTATACG), free and complexed with the intercalating drug daunorubicin, are presented as examples of a series of similar deoxyoctanucleotides with varying base sequences. The spectra are qualitatively interpreted on the basis of previous assignments and on ab initio calculations of the nucleic acid bases and base pairs. (C) 1997 Elsevier Science B.V.

引用

页码：315 / 318

页数：4

共 14 条

[1] FTIR STUDY OF SPECIFIC BINDING INTERACTIONS BETWEEN DNA MINOR GROOVE BINDING LIGANDS AND POLYNUCLEOTIDES [J].