IR-spectroscopic studies of divalent metal ion effects on DNA hydration

被引：24

作者：

Andrushchenko, VV ^{[1
]}

Kornilova, SV ^{[1
]}

Kapinos, LE ^{[1
]}

Hackl, EV ^{[1
]}

Galkin, VL ^{[1
]}

Grigoriev, DN ^{[1
]}

Blagoi, YP ^{[1
]}

机构：

[1] UKRAINIAN ACAD SCI,INST LOW TEMP PHYS & ENGN,UA-310164 KHARKOV,UKRAINE

来源：

JOURNAL OF MOLECULAR STRUCTURE | 1997年 / 408卷

关键词：

IR-spectroscopy; DNA; divalent metal ions; hydration;

D O I：

10.1016/S0022-2860(96)09672-X

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The metal (Mn2+, Ca2+, Cu2+) ion effect on the DNA structure in films is studied at different relative humidities (5-98%) by IR-spectroscopy. The results obtained suggest the interaction of the ions both with the DNA phosphate groups and with the nucleic bases. The formation of the secondary structure of DNA complexed with metal ions is shown to take place at a greater number of water molecules bound to the polymer than it is the case of DNA without ions. The interaction of DNA with metal ions inhibits its transition into the A form and induces essential changes in the hydration energy. (C) 1997 Elsevier Science B.V.

引用

页码：225 / 228

页数：4

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