Death in bathtub revisited with molecular genetics:: a victim with suicidal traits and a LQTS gene mutation

被引：11

作者：

Lunetta, P

Levo, A

Männikkö, A

Penttilä, A

Sajantila, A

机构：

[1] Univ Helsinki, Dept Forens Med, FIN-00014 Helsinki, Finland

[2] Provincial State Off So Finland, Helsinki 00300, Finland

来源：

FORENSIC SCIENCE INTERNATIONAL | 2002年 / 130卷 / 2-3期

关键词：

bathtub; drowning; suicide; long-QT syndrome;

D O I：

10.1016/S0379-0738(02)00379-1

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 [法学]; 10 [医学];

摘要：

A 44-year-old woman with a medical history of mental disorders and previous suicidal behaviour was found in a bathtub and pronounced death few minutes later despite of resuscitation attempts. After police investigation and on the basis of autopsy findings, the death was classified as suicide drowning. Retrospective examination of clinical data revealed, a prolonged rate-corrected QTinterval (QTc: 468 ms) 3 months before death. Post-mortem (PM) DNA analysis disclosed KCNH2(FIN) mutation for the long-QT syndrome (LQTS). The value of PM molecular screening for LQTS is emphasised, especially for victims of putative drowning. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：122 / 124

页数：3

共 22 条

[1]

Molecular diagnosis of the inherited long-QT syndrome in a woman who died after near-drowning [J].