Regioselective synthesis of (trifluoromethyl)-beta-chloroenones

被引：11

作者：

Alvernhe, G ^{[1
]}

Bensadat, A ^{[1
]}

Ghobsi, A ^{[1
]}

Laurent, A ^{[1
]}

Laurent, E ^{[1
]}

机构：

[1] UNIV ORAN ES SENIA,LAB CHIM & ELECTROCHIM ORGAN,ORAN,ALGERIA

来源：

JOURNAL OF FLUORINE CHEMISTRY | 1997年 / 81卷 / 02期

关键词：

Vilsmeier's and related reactions; regioselectivity; unsymmetrical diketones; beta-chloro-(trifluoromethyl)enones;

D O I：

10.1016/S0022-1139(96)03523-3

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The regioselectivity of the conversion of 1,3-diketones into beta-chloroenones can be changed by the appropriate choice of the reagent: reaction with ''Vilsmeier's reagent'' prepared from POCl3 and dimethylformamide or treatment of the diketone with the oxalyl chloride in the presence of dimethylformamide.

引用

页码：169 / 172

页数：4

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