Chiral cyclic beta-amino esters .2. Synthesis by diastereoselective reduction of enamino esters

被引：28

作者：

Blot, J

Bardou, A

Bellec, C

FargeauBellassoued, MC

Celerier, JP

Lhommet, G

Gardette, D

Gramain, JC

机构：

[1] UNIV PARIS 06,LAB CHIM HETEROCYCLES,CNRS,F-75252 PARIS 05,FRANCE

[2] UNIV CLERMONT FERRAND,LAB CHIM SUBST NAT,CNRS,F-63177 AUBIERE,FRANCE

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 49期

关键词：

D O I：

10.1016/S0040-4039(97)10301-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Catalytic and chemical reductions of chiral pyrrolidine beta-enamino esters provides corresponding beta-amino esters with good to moderate diastereomer excesses. The unexpected major diastereomer 5 comes from a reduction process which amounts to an anti hydrogen addition. (C) 1997 Elsevier Science Ltd.

引用

页码：8511 / 8514

页数：4

共 15 条

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