Synthesis of spiro[benzopyrazolonaphthyridine-indoline]-diones and spiro[chromenopyrazolopyridine-indoline]-diones by one-pot, three-component methods in water

被引：61

作者：

Ahadi, Somayeh ^{[1
]}

Ghahremanzadeh, Ramin ^{[1
]}

Mirzaei, Peiman ^{[1
]}

Bazgir, Ayoob ^{[1
]}

机构：

[1] Shahid Beheshti Univ GC, Dept Chem, Tehran, Iran

来源：

TETRAHEDRON | 2009年 / 65卷 / 45期

关键词：

4-Hydroxy-1-methylquinolin-2(1H)-one; Coumarin; Isatin; Pyrazole; Spirooxindole; MULTICOMPONENT REACTIONS; BIOLOGICAL-ACTIVITY; EFFICIENT SYNTHESIS; AQUEOUS-MEDIUM; DERIVATIVES; CHEMISTRY; SPIROOXINDOLES; INHIBITORS; ISATINS; AGENTS;

D O I：

10.1016/j.tet.2009.09.009

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学];

摘要：

The synthesis of spiro[benzo[h]pyrazolo[3,4-b][1,6]naphthyridine-7,3'-indoline]-2',6(5H)-diones and spiro[chromeno[4,3-b]pyrazolo[4,3-e]pyridine-7,3'-indoline]-2',6(6aH,10H)-diones via a one-pot, three-component reaction of 4-hydroxycoumarin or 4-hydroxy-1-methylquinolin-2(1H)-one, isatins and 1H-pyrazol-5-amines in water is reported. (c) 2009 Elsevier Ltd. All rights reserved.

引用

收藏

页码：9316 / 9321

页数：6

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