Efficient interstrand excess electron transfer in PNA:DNA hybrids

被引：35

作者：

Cichon, MK ^{[1
]}

Haas, CH ^{[1
]}

Grolle, F ^{[1
]}

Mees, A ^{[1
]}

Carell, T ^{[1
]}

机构：

[1] Univ Marburg, Dept Chem, D-35032 Marburg, Germany

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2002年 / 124卷 / 47期

关键词：

D O I：

10.1021/ja0277733

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

PNA:DNA strands were prepared containing a flavin electron donor and a thymine dimer acceptor, which gives a strand break upon single electron reduction. With these constructs, it was confirmed that an excess electron transfer through the base stack can be efficient in an interstrand fashion. The effect of an increased distance, a changed sequence, and stacking was explored. Copyright © 2002 American Chemical Society.

引用

页码：13984 / 13985

页数：2

共 23 条

[1]

Behrens C., 2002, ANGEW CHEM INT EDIT, V114, P1841

[2] Influence of intervening mismatches on long-range guanine oxidation in DNA duplexes [J].