The natural history of cervical HPV infection: unresolved issues

被引：736

作者：

Woodman, Ciaran B. J. ^{[1
]}

Collins, Stuart I.

Young, Lawrence S.

机构：

[1] Univ Birmingham, Inst Canc Studies, Canc Res UK, Birmingham B15 2TT, W Midlands, England

[2] Univ Birmingham, Canc Res UK, Clin Trials Unit, Birmingham B15 2TT, W Midlands, England

来源：

NATURE REVIEWS CANCER | 2007年 / 7卷 / 01期

关键词：

D O I：

10.1038/nrc2050

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The identification of high-risk human papillomavirus (HPV) types as a necessary cause of cervical cancer offers the prospect of effective primary prevention and the possibility of improving the efficiency of cervical screening programmes. However, for these opportunities to be realized, a more complete understanding of the natural history of HPV infection, and its relationship to the development of epithelial abnormalities of the cervix, is required. We discuss areas of uncertainty, and their possible effect on disease prevention strategies.

引用

页码：11 / 22

页数：12

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