CNF combination as adjuvant treatment in breast cancer patients is well tolerated

被引:7
作者
Hirvikoski, PP [1 ]
Kumpulainen, EJ [1 ]
Johansson, RT [1 ]
机构
[1] KUOPIO UNIV HOSP,DEPT ONCOL,SF-70211 KUOPIO,FINLAND
关键词
adjuvant; breast; chemotherapy; cyclophosphamide; fluorouracil; neoplasm; mitoxantrone; side effects;
D O I
10.1097/00001813-199704000-00010
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
in this study 194 women with breast cancer received adjuvant CNF combination therapy (cyclophosphamide, mitoxantrone and 5-fluorouracil), The side effects and acute toxicity of the regimen were recorded, Although myelosuppression is the dose-limiting factor of the CNF regimen, it was well tolerated and side effects were limited. This regimen induced no cardiotoxicity or irreversible alopecia. It is concluded that CNF is suitable as adjuvant chemotherapy for breast cancer patients.
引用
收藏
页码:376 / 378
页数:3
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