Etiology of Parkinson's disease: Genetics and environment revisited

被引：58

作者：

Steece-Collier, K

Maries, E

Kordower, JH ^{[1
]}

机构：

[1] Rush Presbyterian St Lukes Med Ctr, Dept Neurol Sci, Chicago, IL 60612 USA

[2] Chicago Med Sch, Dept Neurosci, N Chicago, IL 60064 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 2002年 / 99卷 / 22期

关键词：

D O I：

10.1073/pnas.242594999

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：13972 / 13974

页数：3

共 40 条

[1] Mice lacking α-synuclein display functional deficits in the nigrostriatal dopamine system [J].

Abeliovich, A ;

Schmitz, Y ;

Fariñas, I ;

Choi-Lundberg, D ;

Ho, WH ;

Castillo, PE ;

Shinsky, N ;

Verdugo, JMG ;

Armanini, M ;

Ryan, A ;

Hynes, M ;

Phillips, H ;

Sulzer, D ;

Rosenthal, A .

NEURON, 2000, 25 (01) :239-252

[2] Fibrils formed in vitro from α-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid [J].

Conway, KA ;

Harper, JD ;

Lansbury, PT .

BIOCHEMISTRY, 2000, 39 (10) :2552-2563

[3] Acceleration of oligomerization, not fibrillization, is a shared property of both α-synuclein mutations linked to early-onset Parkinson's disease:: Implications for pathogenesis and therapy [J].

Conway, KA ;

Lee, SJ ;

Rochet, JC ;

Ding, TT ;

Williamson, RE ;

Lansbury, PT .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (02) :571-576

[4]

Conway KA, 2000, ANN NY ACAD SCI, V920, P42

[5] Kinetic stabilization of the α-synuclein protofibril by a dopamine-α-synuclein adduct [J].

Conway, KA ;

Rochet, JC ;

Bieganski, RM ;

Lansbury, PT .

SCIENCE, 2001, 294 (5545) :1346-1349

[6] Resistance of α-synuclein null mice to the parkinsonian neurotoxin MPTP [J].

Dauer, W ;

Kholodilov, N ;

Vila, M ;

Trillat, AC ;

Goodchild, R ;

Larsen, KE ;

Staal, R ;

Tieu, K ;

Schmitz, Y ;

Yuan, CA ;

Rocha, M ;

Jackson-Lewis, V ;

Hersch, S ;

Sulzer, D ;

Przedborski, S ;

Burke, R ;

Hen, R .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (22) :14524-14529

[7] Aggregates from mutant and wild-type α-synuclein proteins and NAC peptide induce apoptotic cell death in human neuroblastoma cells by formation of β-sheet and amyloid-like filaments [J].

El-Agnaf, OMA ;

Jakes, R ;

Curran, MD ;

Middleton, D ;

Ingenito, R ;

Bianchi, E ;

Pessi, A ;

Neill, D ;

Wallace, A .

FEBS LETTERS, 1998, 440 (1-2) :71-75

[8] A Drosophila model of Parkinson's disease [J].

Feany, MB ;

Bender, WW .

NATURE, 2000, 404 (6776) :394-398

[9] AGING AND PARKINSONS-DISEASE - SUBSTANTIA-NIGRA REGIONAL SELECTIVITY [J].

FEARNLEY, JM ;

LEES, AJ .

BRAIN, 1991, 114 :2283-2301

[10] CHARACTERIZATION OF A NOVEL PROTEIN REGULATED DURING THE CRITICAL PERIOD FOR SONG LEARNING IN THE ZEBRA FINCH [J].

GEORGE, JM ;

JIN, H ;

WOODS, WS ;

CLAYTON, DF .

NEURON, 1995, 15 (02) :361-372

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