Evaluation of Intravenous Paracetamol Administration on Postoperative Pain and Recovery Characteristics in Patients Undergoing Laparoscopic Cholecystectomy

Purpose: In this study, the effects of intravenous paracetamol treatment on early postoperative period analgesia and recovery characteristics after laparoscopic cholecystectomy have been evaluated. Methods: Forty patients whose American Society of Anesthesiologists physical status I or 11 underwent laparoscopic cholecystectomy and randomly divided into 2 equal groups. In the first group, 1 g paracetamol was given to the patients intravenously after intubation before start of the Surgery in 15 minutes. The 100 mL 0.9% NaCl was infused intravenously for the control group in 15 minutes. Postoperative pain was evaluated and recovery characteristics were evaluated. Results: Verbal and Visual pain scores of the paracetamol group were significantly lower than control group (P<0.05). First morphine requirement and total administered morphine dose and duration of staying in recover), room were significantly decreased in the paracetamol group (P<0.05). Conclusions: Beside its effective analgesic properties, paracetamol administration during per operative period supports effective and faster recovery.