Interleukin 16: implications for CD4 functions and HIV-1 progression

被引：46

作者：

Center, DM ^{[1
]}

Kornfeld, H ^{[1
]}

Ryan, TC ^{[1
]}

Cruikshank, WW ^{[1
]}

机构：

[1] Boston Univ, Sch Med, Evans Mem Dept Med, Boston, MA 02118 USA

来源：

IMMUNOLOGY TODAY | 2000年 / 21卷 / 06期

关键词：

D O I：

10.1016/S0167-5699(00)01629-7

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In this article, David Center and colleagues clarify the controversies thai have emerged over the unique structure of interleukin it and its anti-HIV-1 activity. Interleukin 16 is a ligand for CD4, and this implies CD4 acts as a sentinel receptor that can switch CD4(+) T cells between immune and inflammatory functions.

引用

页码：273 / 280

页数：8

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